Polynucleotides

Advanced Skin Regeneration from Within

Polynucleotides are an innovative injectable treatment designed to deeply rejuvenate and repair the skin at a cellular level. Derived from filtered, purified fragments of DNA (typically from salmon), they stimulate tissue repair, improve skin quality, and promote long-term hydration. Unlike dermal fillers, they don’t add volume — instead, they work biologically to restore your skin’s natural structure and vitality.

Benefits of Polynucleotides

  • Boosts collagen and elastin production

  • Improves skin texture, tone, and elasticity

  • Reduces inflammation and oxidative stress

  • Softens dark circles and fine lines around the eyes

  • Ideal for delicate areas like under eyes, face, neck, and décolletage

  • Biocompatible and safe — no added volume or harsh chemicals

  • Non-invasive: The treatment is minimally invasive, making it suitable for those looking for natural rejuvenation without surgery.

  • Natural Composition: As a natural substance, polynucleotides are well-tolerated by the body, minimizing the risk of adverse reactions.

  • Versatile Application: They can be used on various areas, including the face, neck, and around the eyes, addressing multiple skin concerns.

  • Long-lasting Results: Effects can often be seen immediately and may improve over time as the skin continues to regenerate.

What are Polynucleotides?

Polynucleotides are naturally occurring molecules composed of long chains of nucleotides, which are the building blocks of DNA and RNA. In the context of skincare, polynucleotides are used for their regenerative properties, promoting cellular repair, hydration, and overall skin health. They are particularly effective in enhancing skin structure and function, making them a popular choice for aesthetic treatments aimed at rejuvenating the skin and delicate areas around the eyes.

How Much Does It Cost?

A regenerative injectable treatment promoting skin cell repair and anti-ageing benefits. Ideal for under-eye, face, and décolletage rejuvenation.

- Polynucleotide eyes £120

- Polynucleotide full face £170

How Polynucleotides Work

Once injected into targeted areas, polynucleotides begin working immediately to repair damaged tissue and stimulate fibroblast activity. This triggers a natural healing response — boosting collagen, improving hydration, and strengthening the skin barrier from within. Results develop gradually and continue to improve over several weeks, with optimal results usually seen after a course of 2–3 sessions.

Polynucleotides are suitable for all skin types and are especially effective for early signs of ageing, dull or stressed skin, and sensitive areas that require gentle but powerful rejuvenation.

Polynucleotides work by stimulating the body’s natural healing processes. They help to:

1.⁠ ⁠Promote Cell Regeneration: By enhancing cellular turnover, polynucleotides aid in the repair of damaged skin, leading to a more youthful appearance.

2.⁠ ⁠Boost Hydration: They have a unique ability to retain moisture, which helps to keep the skin plump and hydrated.

3.⁠ ⁠Stimulate Collagen Production: Polynucleotides encourage collagen synthesis, improving skin elasticity and reducing the appearance of fine lines and wrinkles.

4.⁠ ⁠Enhance Skin Texture: The regenerative properties of polynucleotides improve skin texture, resulting in a smoother and more even complexion.

5.⁠ ⁠Support Eye Area Health: When applied to the delicate skin around the eyes, polynucleotides can reduce puffiness, dark circles, and fine lines, providing a refreshed, youthful look.

Pre-Care for Polynucleotide Treatments

1.⁠ ⁠Consultation: Schedule a consultation with a qualified practitioner to discuss your goals, medical history, and any skin concerns.

2.⁠ ⁠Avoid Blood Thinners: Stop taking blood-thinning medications or supplements (like aspirin, ibuprofen, or vitamin E) for at least 48 hours before treatment to minimise bruising.

3.⁠ ⁠Stay Hydrated: Drink plenty of water in the days leading up to your appointment to ensure optimal skin hydration.

4.⁠ ⁠Limit Alcohol Consumption: Avoid alcohol for at least 24 hours prior to treatment, as it can increase the risk of swelling and bruising.

5.⁠ ⁠Sun Protection: Minimise sun exposure and avoid tanning (both natural and artificial) for at least a week before treatment to reduce skin sensitivity.

6.⁠ ⁠Inform Your Practitioner: Disclose any medications, allergies, or skin conditions to your practitioner.

Aftercare for Polynucleotide Treatments

1.⁠ ⁠Avoid Touching the Area: Refrain from touching or rubbing the treated area for at least 24 hours to prevent irritation or displacement of the product.

2.⁠ ⁠Stay Hydrated: Continue to drink plenty of water to support skin hydration and promote optimal healing.

3.⁠ ⁠Avoid Heat Exposure: Limit exposure to saunas, hot tubs, or intense workouts for at least 48 hours to minimize swelling and redness.

4.⁠ ⁠Sun Protection: Protect your skin from direct sunlight and apply a broad-spectrum sunscreen to prevent UV damage, as the skin may be more sensitive post-treatment.

5.⁠ ⁠Skip Makeup: Avoid applying makeup for at least 24 hours to allow the skin to heal properly and reduce the risk of irritation.

6.⁠ ⁠Monitor for Side Effects: Be aware of potential side effects, such as minor swelling, redness, or tenderness at the injection sites. These are typically temporary and should resolve within a few days.

7.⁠ ⁠Avoid Other Treatments: Refrain from other facial treatments, such as chemical peels or microdermabrasion, for at least two weeks after your treatment.

8.⁠ ⁠Follow-Up Appointment: Schedule a follow-up appointment with your practitioner as recommended to assess your results and discuss any additional treatments if necessary.

By incorporating polynucleotides into your skincare routine, you can harness their regenerative properties to achieve healthier, more youthful-looking skin, particularly in sensitive areas like the eyes. Following the pre-care and aftercare guidelines will help ensure the best possible results from your treatment.

Ready to Feel Your Best?

Enhance your natural beauty with expert treatments tailored to you.

Whether you're booking your first appointment or returning for a refresh, you're in trusted hands.

2025 © Cocoon by Zoe - Terms | Privacy | Contact - SalesMasterHub